Logistic assignment Essay Example | Topics and Well Written Essays - 5000 words

Logistic assignment - Essay Example In future, the group plans to get into the process of higher levels of difficulties. According to the plan, with prior approval of umpire, the company plans to move into level two and then level three. The strategy has both strengths and weaknesses. The strengths of the strategy undertaken by the company at present, is that the company is involved in producing the standardised model. It means the methodologies involved are relatively simpler. So, the production is higher. Also, the cost of holding is comparatively lesser and there are no such wastage of resources for reworks, machine down times and scrap. The cost of labour is much lower in the present level of difficulty. Also, it is found that the semi fixed costs are also lower in the first level of difficulty. As the products are standardised, the demand of the products are also higher by almost double. Apart from the strengths, there are also many weaknesses related with the present strategy. As the present strategy caters to the standard model of products, the market is getting to be extinct sooner or later. Therefore, the company have to diversify into advanced models. Also, in the present strategy, the production capacity is lower. As there were both positives as well as negatives for the present strategy, the manufacturing group is moving towards the developed strategy which includes modern concepts like that of forecasting, scheduling and capacity. Forecasting – Though often thought to be alike and confused, forecasting is much different from goal. Forecasting is the way to predict the happenings in the future. Forecasting is part of the decision making mechanism of the company. The major implementation of the function of forecasting is that in the inventory control, requirements of manpower and the selection of capacity and the location of facility (Loerch, n.d.). It is good for the manufacturing group that it has incorporated forecasting with in the future

Physical Science Essay Example | Topics and Well Written Essays - 250 words - 3

Physical Science - Essay Example This situation could be reversed and normal operation restored after diagnosing the problem. In this context, the portable room heater needs to have high resistance so as to be effective in emission of heat. As such, a high current would be required for this function. The high current demanded by the heater would cause a high flow of current in the electric connection in the room. The circuit breaker exposed to the high current would cause the metal strip in it to warm up and bend away, breaking the circuit connection in the room, breaking normal electric supply which causes the lights to go off. Similarly, the metal strip in the circuit breaker could be of too low resistance. As such, it fails to contain the flow of current required for normal operation of the room heater. As such, any slight rise in the current above what sustains lighting of the bulbs in the room would exceed its resistance threshold, warming up the metal strip causing it to bend away from the circuit and breaking the electric connection and the lights go

Psychology Essay Example for Free

Psychology Essay Psychodynamic: One advantage of psychodynamic therapy is the relationship that is formed between the psychologist and the patient. The patient is able to form trust in the psychologist which makes it easier for them to talk about their problems. Another advantage is the ability for the psychologist to give a human opinion. They can tell the client what they think is best for them specific to the client’s needs. Client-centered: The advantage of this is the fact that the client is the one to guide him or herself. The psychologist is only there to channel the person’s thoughts but not to judge, direct, or interpret them. Secondly, this procedure is very encouraging. It gives the client a feeling of acceptance and makes them think that there is hope to be cured. Counterconditioning: An advantage of counterconditioning is that it makes the person face the fear that consumes them. In exposure therapies, the person is put in the situation that he or she fears and is forced to face it and act in a calm manor. The second advantage would be that the person is conditioned to shy away from a problem. An unwanted response is paired with a problem (such as an addiction) which will make the person not want to go back to that problematic item. Cognitive-behavioral: The advantage of this psychotherapy is that incorporates the functioning of the brain and finding out how they can change its function to change the mood of the patient. This goes onto more of a biological level, providing treatment that can be administered medically instead of only speaking to a psychologist. The other advantage of this is that it will alter the way the person acts altogether. They will become calm if they are anxious and or make people aware of their negativity and teach them to replace it with positive thoughts.

The Dna Extraction Essay Example for Free

The Dna Extraction Essay 1. The salt contributes positively charged atoms that neutralise the normal negative charge of DNA. Salt is used at a high molarity due to the fact that it precipitates all of the proteins out. DNA is insoluble in low molar salt solutions but soluble in low molar salt solutions thus keeping the DNA in solution. 2. blending the onion will homogenize the mixture and it helps with the breakdown of the cell walls. Blending saves one the time and effort of using a motar and pestle, however it may break a lot of the DNA which is not favourable as one needs a lot of DNA for the extraction. 3. The enzymes in the soap are used to break down the lipid (fat) molecules of the cells nuclear membranes releasing the contents of the cell crucially including the DNA. These enzymes in the soap are what break down grease while washing dishes. 4. The DNA does not dissolve in this alcohol but rather pushes up through and out of the solution or precipitates. It is less dense than water or cell scum which is what settles to the bottom of the glass so it floats up into the alcohol layer, where you see it as a snotty, string-like substance, with small bubbles formed on it. 5. Because protein is stored in them for the nutrition of the new plants. 6. It is too small to be seen with the naked eye. What you extracted is millions of strands of DNA. In addition to that, whilst the substance was heated, the DNA got denatured which results in it looking more like a ladder than a helix. 7. Most of the DNA extracted during this proccess comes from the nucleus of the cell. AIM: The purpose of this experiment is to extract DNA from a variety of cells (Onion cells in particular) and see DNA molecules. This will show that, contrary to popular opinion, DNA is not just found in blood cells, but in a variety of tissues. Prior knowledge should include the fact that cell membranes are layers of lipids, or fat molecules, that DNA is found in the nucleus of a cell, and that enzymes speed up chemical reactions. HYPOTHESIS: DNA is present in the cells of all living organisms. METHOD: 1. Prepare two water baths one at 60Â °C and another filled with ice and water, around 4Â °C. For the hot water bath, a large metal pot can be used along with a thermometer with an appropriate temperature range. For the ice bath, a mixing bowl filled with ice and water works well. 2. For each onion, make a solution consisting of 10 ml of liquid dishwashing detergent and 1.5 g of table salt. Put in a 250 ml beaker and emulsify. 3. Add distilled water to make a final volume of 100 ml. Dissolve the salt by stirring slowly to avoid foaming. 4. Coarsely chop one large onion with a food processor or blender and put into a 1000 ml mixing bowl. For best results, do not chop the onion too finely. The size of the pieces should be like those used in making spaghetti. It is better to have the pieces too large than too small. 5. Cover chopped onion with the 100 ml of solution from step 2. The liquid detergent causes the cell membrane to break down and dissolves the lipids and proteins of the cell by disrupting the bonds that hold the cell membrane together. The detergent causes lipids and proteins to precipitate out of the solution. Salt enables nucleic acids to precipitate out of an alcohol solution because it shields the negative phosphate end of DNA, causing the DNA strands to come closer together and coalesce. 6. Put the measuring cup in a hot water bath at 60Â °C for 10-12 minutes. During this time, press the chopped onion mixture against the side of the measuring cup with the back of the spoon. (Do not keep the mixture in the hot water bath for more than 15 minutes because the DNA will begin to break down.) If using a large metal pot for water bath, remove the pot from the stove before placing the onion-containing measuring cup inside—the procedure is safer if the pot is off the burner. Cont inue to monitor temperature of water bath and make adjustments as needed. 7. The heat treatment softens the phospholipids in the cell membrane and denatures the DNAse enzymes which, if present, would cut the DNA into small fragments so that it could not be extracted. 8. Cool the mixture in an ice water bath for 5 minutes. During this time, press the chopped onion mixture against the side of the measuring cup with the back of the spoon. This step slows the breakdown of DNA. 9. Filter the mixture through a #6 coffee filter or four layers of cheese cloth placed in a strainer over a 4-cup measuring cup. When you filter the onion mixture, try to keep the foam from getting into the filtrate. It sometimes filters slowly, so you might want to put the whole set up in the refrigerator and let it filter overnight. 10. Dispense the onion solution into a test tube. The test tube should contain about 1 teaspoon of solution or be about 1/3 full. For most uniform results among test tubes, stir the solution frequently when dispensing it into the tubes. There is not an adva ntage to dispensing more than one teaspoon of solution into a test tube. The solution can be stored in a refrigerator for about a day before it is used for the laboratory exercise. When the solution is removed from the refrigerator, it should be gently mixed before the test tubes are filled. 11. Add cold alcohol to the test tube to create an alcohol layer on top of about 1 cm. For best results, the alcohol should be as cold as possible. The alcohol can be added to the solution in at least three ways: (a) Fill a pasteur pipette with alcohol, put it to bottom of the test tube, and release the alcohol. (b) Or, put about 1 cm of alcohol into the bottom of a test tube and add the onion solution. (c) Or, slowly pour the alcohol down the inside of the test tube with a pasteur pipette or medicine dropper. DNA is not soluble in alcohol. When alcohol is added to the mixture, all the components of the mixture, except for DNA, stay in solution while the DNA precipitates out into the alcohol layer. 1 2. Let the solution sit for 2-3 minutes without disturbing it. It is important NOT to shake the test tube. You can watch the white DNA precipitate out into the alcohol layer. When good results are obtained, there will be enough DNA to spool on to a glass rod, a pasteur pipette that has been heated at the tip to form a hook, or similar device. A wooden skewer or nut pick (small metal rod with curved tip) may also work well for spooling DNA if Pasteur pipette is unavailable. DNA has the appearance of white mucus. CONCLUSION: With these findings we can conclude that DNA is present and can be found in the cells of all living organisms and not just in those of the human body.

Optical Sensors for Biological and Chemical Measurement

Optical Sensors for Biological and Chemical Measurement This Literature review is divided into three main parts. They are, Surface Plasmon Resonance, BIACORE 3000 and Winspall. In these three mechanism, Surface Plasmon Resonance stood a basic platform for optical bio- sensing whereas BIACORE 3000 is an extended version. On the other hand, Winspall is a special software used to simulate the reflectivity curves. The first part of the literature review is Surface Plasmon Resonance which explains the basic concept, sensors used in SPR and application in major areas. And also the future trend of Surface Plasmon Resonance sensors has been explained. Similarly the next section has a detailed structure of BIACORE 3000 describing its sensitivity and throughput along with new instrument software. As mention above that Winspall is a special software, it has been clearly discussed in third part. In this discussion, how the reflectivity curve is simulated with the help of Winspall software is explained with taking as an example of Reflection at air- g lass interface. Surface Plasmon Resonance (SPR) Introduction: For the past two decades there is a massive increase in the field of research and development of optical sensors for the measurement of chemical and biological quantities. Measuring CO2 and O2 Concentration were developed by optical chemical sensors which is the first optical device based on the measurement changes in absorption spectrum (Lubbers, et al. 1975). The chemical sensors and biosensors use various optical methods such as Ellipsometry, Interferometry, Spectroscopy and Surface Plasmon Resonance (SPR). In these sensors a required amount is determined by measuring the refractive index, absorbance and fluorescence properties of analyte molecules (Wolfbeis et al., 1991). In late seventies, the potential of Surface Plasmon Resonance (SPR) for characterization of thin films (Pockrand et al., 1978) and monitoring processes at metal interfaces (Gordon II et al., 1980) had been recognized. In 1982, Nylander and Liedberg demonstrated the typical use of SPR for gas detection and bio-se nsing (Nylander et al., 1982). For the measurement of physical, chemical and biological quantities new SPR sensing configuration as well as application of SPR- sensing devices were developed since from the scientific community SPR had received continuously growing attention. In optical bio- sensing more than 75% of the research are based on the SPR, and SPR sensors are used commercially by several leading organizations in the field of direct real- time observation of the bio- molecular interactions. What is meant by SPR: SPR has many practical applications in sensitive detectors and it is having the ability to detect sub-monomolecular coverage. This phenomenon was first observed by Wood in 1902 (Wood, 1902), according to him, SPR is a pattern of anomalous dark and light bands in the reflected light when the light is polarised on a mirror with a diffraction grating on its surface. And the phenomenon of physical interpretation was initiated by Lord Rayleigh (Rayleigh, 1907) and additionally it was enhanced (Fano et al., 1941) but since 1968 there is no detail and complete explanation of the phenomenon. In the same year Otto (Otto, et al. 1969) and Kretschmann and Raether (Kretschmann, et al., 1968) reported in detail about the excitation of surface Plasmons. Optical chemical sensors and biosensors in SPR: Usually, an Optical sensor is a transducing medium which correlates the optical and bio- chemical domains and the system which supports the optoelectronic components of an electronic system and allowing data processing. The transducing medium converts the quantity of interest change into refractive index change which may be estimated by optically interrogating the SPR. The SPR sensor of an optical system contain two parts, one is the source of optical radiation and another one is the optical structure in which surface Plasma Waves (SPW) is excited and interrogated. In this SPR interrogation process, the electronic system process and generates the electronic signal and the properties of sensors subsystem only determines the major properties of an SPR sensor. The properties of an optical system and the transducing medium is dependent to the sensor sensitivity, stability and resolution whereas the selectivity and response time of the sensor are mostly estimates by the properties of tran sducing medium. Technologies and materials used in SPR-sensing devices: There are various technologies employed in the fabrication of SPR sensors since SPR chemical sensing and bio- sensing has multidisciplinary nature. But in particular there are two technologies which are considered as most important on the fabrication of SPR sensors. They are the fabrication of the optical part of the sensing element and preparation of Opto- chemical transducing medium. Application of SPR sensors in major areas: Measurement of physical quantities in SPR Based upon the sensitivity of SPR to the momentum of the incident light wave the displacement (Margheri et al., 1996) and angular position of SPR sensors is measured. For the development of SPR -sensing devices various optical transducing materials have been exploited including the refractive index changes of porous thin layers and polymers (Weiss et al., 1996) by humidity sensor and a temperature sensor based on the thermo- optic effect (Chadwick, 1993). SPR chemical sensing: Direct measurement of refractive index using an SPR sensor can be achieved by complexity variation in the concentration of analyte and due to the adsorption or chemical reaction of an analyte with a transducing medium the measurement of SPR variation are dependent to chemical SPR sensors which results in changes in its optical properties. Surface Plasmon Resonance Bio- sensing In 1983, the first application of SPR to bio- sensing was demonstrated (Liedberg, 1983), previously the demonstration was carried out and developed by some other groups (Flanagan et al., 1984). The real time bio- specific interaction analysis method was the first survey on Surface Plasmon Resonance which is appeared on 1994 (Lundstrà ¶m, 1994) frequently used and continuously improved for examination of kinetic and thermodynamics constants of bio- molecular interactions. The direct detection of binding reaction is used for the purpose of analyte quantification, however, the adsorption of small molecules produces the increase in refractive index which is not sufficient to detect directly. Commercialization of Surface Plasmon Resonance sensor technology: The first commercial SPR bio- sensor was launched on 1990 by Swedish BIAcore AB which leads to systematic development of SPR bio- sensor technology. Then the BIAcore sensor technology has been further developed in terms of speed, throughput and accuracy. At present BIAcore offers a number of models of SPR bio- sensors (BIACORE 3000, BIACORE 2000, BIACORE X, BIACORE 1000, BiacoreQuant) (Sinclair et al., 1990). By further growth of commercialisation of optical bio- sensor system results in the development of another SPR bio- sensor system (TI- SPR- 1Experimenters Kit, Spreeta Evaluation Kit) by Texas Instrument in USA [127]. There is another SPR bio- sensor system called Kinetic instrument 1 which has been developed by Bio TuL Bio Instruments GmbH (Germany). The recent SPR sensor which is commercially available is waveguide- based device using wavelength interrogation in a multimode optical fibre developed by EBI sensors (Washington, USA). Future trends in development of Surface Plasmon Resonance sensors Even though SPR is used in many fields, there is a necessity for detection and analysis of chemical and bio- chemical substances in many significant areas such as medical, environmental monitoring, bio- technology, drug and food monitoring. SPR sensor technology holds potential for applications in the mentioned areas. At present SPR bio- sensors devices compete with other types of bio- sensors (Owen, 1997) and the currently available bio- sensors covers only some degree of area of (bio) chemical monitoring market aiming primarily at research and analytical laboratories. So, a new SPR bio- sensor is need to compete the existing system to cover the specialised laboratories and testing sites on the basis of factor such as cheap, ease of use, robustness, sensitivity and stability. Conclusion For the past 10 years there is a great improvement in Surface Plasmon Resonance sensors technology with many numbers of applications. Even more the SPR sensors technology will get growth and extend in the usage by developing new type of bio- sensors which competes the existing system and also designing low- cost, allow sensitive and fast in speed. BIAcore 3000 Introduction For label free studies of bio- molecular binding, BIAcore 3000 is considered as highest performance research system which is existing currently. The substances such as lipid vesicles, viruses, bacteria and eukaryotic cells which are ranging from small molecules to crude extracts can be studied. Speed, strength and specificity of binding and determination of active concentration of components questions have been answered by BIAcore 3000 and it is an ideal tool for functional proteomics. For the future trends, there are lot to invent technically which has to meet the highest demands for efficiency, sensitivity and flexibility. The awareness and experience of BIAcore 3000 is an effective guide for the users without effort through preparation, evaluation and experimentation has been incorporated into Wizards. This BIAcore 3000 follows the C- language Conditional IF/THEN statements to response perfectly to changes in run conditions, since it provide a trend analysis and preliminary result s at the end of runs. For an individual sample characterisation BIAcore 3000 is used to design, where the highest resolution in kinetic analysis and automation of multi- sample analyses is crucial and it provides a superior performance for kinetic analysis. Highest signal to noise ratio and a high data acquisition achieves increased resolution. BIACORE 3000 represents the logical next step in the development of BIACORE systems for sophisticated binding studies, with better sensitivity, higher throughput, improved liquid flow properties and an easier software interface than previous system in the series (Francis, 1998). High sensitivity BIAcore has an working range as little as 10 RU, but it can be able to detect up to 70000 RU (one RU is equivalent to one picogram protein per square millimetre on the sensor surface) and also it has highest sensitivity to monitor the bio- molecular binding which ensures in the interpretation of related kinetic data and in the detection of binding events. The molecular weights of the binding partners and experimental conditions are dependent to the measurement of kinetic and affinity parameters. The controlled experimental conditions ensure precisely in the design of micro- fluidic pathway and in the detection system of BIAcore 3000. By comparing to other BIAcore systems, BIAcore 3000 has the ability to generate twice the signal from the same sample injection time. The micro- fluidic pathway of BIAcore 3000 has four flow cells overlaid in single sensor surface in which the each cell consists with a volume of 0.02  µl. During a single sample injection one cell has used to be as a true reference. The resolution and information from a single run will be maximised by automatic in- line reference subtraction and the signals will be resolved by reducing the background noise. Improved Throughput There is a significant difference in the design of IFC, between BIAcore 3000 and to its predecessors, where the height of the flow cells has been reduced to less than half. This may create some trivial sound, but the binding measurement in the screening application and kinetic analysis has important consequences. The mass transfer of analyte to the surface height is improved by the consequence of the lower flow cell, where as the height is inversely proportional to the mass transfer co- efficient for diffusion controlled transfer. If the height is increased by the factor 2, then the mass transfer co- efficient for diffusion will decreases by factor 1.6. Similarly, we can link this to the practical terms, that is, the faster kinetics can be measured without interference from mass transfer process. It also means that same response is achieved in the shorter time in a mass transfer limited situation in which the sample throughput is increased in screening situations. The improved sensit ivity enhances the gain which allows the system to work at lower relative response levels confidently. Streamlined wash routines between the introduction of new reagent rack and analysis cycles improves the automated analysis situation by throughput which allows 192 wells in two micro- plates to be used for samples. But some users of BIAcore 3000 says that clogging problems in the flow system is due to the reduced flow cell height when particular samples such as crude extracts or whole cell suspension are used. At the same time the users do not report problems when the clogging in micro- flow systems is quoted as an argument in favour of open curvette systems even when the analyses involving whole cells and there is no cause to think that the lower flow cell height in the BIAcore will built important clogging problems (Francis M, 1998). Software The BIAcore 3000 instruments have large improvements technically by introduction of new softwares which is designed to improve the analysis quality and to simplify the operation. Latest versions of the control software BIAcore 2000 have all these features. The BIAcore 2000 and BIAcore 3000 consists two- channel system BIAcore X with line reference subtraction method. Due to this, the users can progress and evaluate their data with confidently and also the data quality improves to large extent. The new IFC (Integrated fluidic cartridge) in the BIAcore 3000 is used to bypass the flow cells and to improve the cost- efficiency of chip operation. The features of BIAcore control software is due to the introduction of application wizards since the application wizard provides step by step information in a clear way to a particular kind of experiment for designing and interpreting the results with on-line help and feedback give the correct chance of achievement. The informations through on-li ne functions and the wizards were created based on the experience of binding studies over the years and it provides a new experience to the users and benefits to the companys expertise. Conclusion In summary, BIAcore 3000 is considered as most advanced system in the series of BIAcore and also it represents the present state of the art in technology for affinity- based bio- sensors. The system will extend the range of applications by the technology with higher sensitivity, improve in sampling handling and enhanced kinetic analysis facilities to cover many of the small molecules like cofactors, signalling substances present in the basic science research and drug candidates in the pharmaceutical industry. For dealing the large amount of high quality data, the refinement of hardware and computer software involved in the BIAcore system can provide and this is considered as a developed approach. Processing the data in the system becomes more and more of a bottle neck since the automated analysis becomes faster and more complicated. Winspall Introduction: To simulate the surface Plasmon resonance curves special software is designed based on the Fresnel formalism which is called as Winspall, developed by A. Scheller at the Max Planck Institute for polymer Research (Chifen, 2007). This software is very easy to use and gives accurate results when simulating the reflection curves (RES- TEC, 2010). Similarly, Winspall software is also used to determine the layer thickness in deposited LB (Langmuir- Blodgett) layers (KSV Inst, 2010). In many practical and commercial application electronic components such as sensors, detectors, displays and circuit boards provides the ability to assemble ordered molecular films with tailored functionality over macroscopic lateral dimensions. This technique is called as Langmuir- Blodgett (LB) deposition. In this deposition, technique the air- water interface contains micro particles and nano particles which are to be compressed and transferred to solid substrate. Here, the Winspall software is used to find t he deposition thickness between the particle layers and also the Fresnel coefficients of each film/ layer with recursion formalism will be calculated (Chifen, 2007). Simulation of Reflectivity curve using Winspall: As mentioned above, Winspall is used to simulate the reflection curves; this section gives a detail view how the reflected curve is simulated using Winspall software with an example. Let us consider an easy prism experiment, base of the prism reflects the laser beam and reflected light is the function of the angle of incidence. Now this reflected curve from the prism is going to be simulating using Winspall. So for this, we need the optical prism constant and air constant. The Winspall software consists of a special simulation parameter table (Fig 2) where the optical comments are to be filled; depending upon the optical parameters the simulation results will be made. For the above example we have to fill the optical components parameter such as prism and air. The first optical parameter is prism; we have to enter the thickness (no 1) 0 for in the table. And then the real and imaginary part of dielectric constant should be filled. The real part of dielectric constant is 2.29 in our example and the imaginary part is zero due to the absence of adsorption in the glass. The second optical component is air (no 2), no thickness and real part of dielectric constant is 1 and imaginary part is zero. Now the simulation parameters are filled in the table. The next step is to click the OK button to get simulation output. Once the OK button is clicked on the simulation parameter window, we will get a simulation curve as an output (Fig 3) for the filled values in the table in separate window. This is the typical curve describes the total internal reflection occurred in the prism and the reflected light separates high index from low index material. In general whenever a light passes through the interface, there will be no reflection at low angles, when the angle gets large the total internal reflection will occur. Below the window shows the simulation output for the values which were filled in the table. This graph explains that below 39 degree there is no reflection, when the angle increases the light get reflects until the total internal reflection is reached. Now to modify or to adjust the reflectivity curve, extra optical components value should be added in the table. In the above case, we are going to add another component between the glass and the air. It is 50 nm thick gold layer with the optical constants Eps-X real=-12.45 and Eps-X imag=1.3. Due to the minor differences in the evaporation process the above mentioned optical constant values for gold varies to some extent. Once these values are entered and we clicked OK button in the simulation parameter window, we will get a curve which is entirely different when compared to previous output (Fig 3). Because of reflective property of gold, first the total internal reflection becomes very thin from 0 to almost 1 and then around 43 degrees a surface Plasmon shows up a strong dip in reflectivity. Due to this strong dip, now the total intensity will jump in this Plasmon and there wont be any part of light reflection occurs. This simulation output curve describes the optical properties of a typical blank substrate used for surface Plasmon measurements. The below shown window consists of simulation output for newer optical component values Now to get real Plasmon and thin layers, a 3nm thick gold layer is added on the top with the dielectric constant of 2.11 (n=1.45) maybe some polymer or a protein. Once the new dielectric constant value in added, there will be a change in the simulation output curve (Fig 4) i.e. the Plasmon resonance shifted a little. We are now about half a degree higher. This shift can be easily measured and for the investigation of such thin layers Surface Plasmon Spectroscopy is well apt. Similarly to get thicker layer 30 nm thick gold layer used on the top which gives result as stronger shift of the Plasmon resonance. But when try to increase the strong shift of Plasmon resonance curve by using 300 nm thick layers a very sharp dip is found in the reflectivity curve at smaller angle. At this smaller a new waveguide mode occurred instead of Plasmon. By increasing the thickness i.e. by adding the thick gold layer with different nm thick on the top we will get more and more waveguides on the reflect ivity spectrum. The below window diagram shows the five waveguide modes in the range for 70 degree for 3 micro meter thick layer. At the same time waveguides can also be found in s-polarised light. This s-polarised light waveguides are also can be simulate by Winspall software. On the other hand, using the Winspall software the Surface Plasmon Resonance curve can be evaluated very easily. This is carried out by the same process, just filling the simulation parameter table. Conclusion: Winspall is special user- friendly software to represent the Surface Plasmon Resonance curves and also it very easy to carry the simulation and evaluation of reflectivity curves.

Hydropower And Wind Potentials In Hong Kong Environmental Sciences Essay

Hydropower And Wind Potentials In Hong Kong Environmental Sciences Essay For decades mankind are in search for new energy resources to deal with the depleting fossil fuel. A lot of renewable energy and associated technologies were developed to assist current energy use to mitigate the imperative energy crisis. The current issues of climate change and global warming accelerated the needs into researches on renewable technologies even more. Hong Kong is a special city with limited energy resources in a densely populated space. Current energy source in Hong Kong mostly rely on imported fossil fuels. The intention of replacing fossil fuel with other alternatives have become clear in both Government and non- Government Organisations. The Energy Efficiency Office (EEO); Electrical, Mechanical Service Department (EMSD), HKSARG has performed a study on feasibilities of various kinds of renewable energy in Hong Kong in 2001 (EMSD, 2001), the study gave an overview on feasibility of Solar, Wind, Fuel cells, Energy-from-Waste, and some other alternative energy. Every technologies was analysed, giving a conclusion that solar will be the most viable renewable energy source. The study of Tidal, and Hydroelectricity, however, was loosely studied due to the belief that they are relatively new technologies. However, although they are not being researched until very recent years, they have been used by human long beyond history. Mills that uses tidal energy has been found in the 12th century (Wallechinsky), whereas the hydro-energy was used even further back to Ancient Greek and Roman, where they use hydro-power for grinding mills (The U.S. Department of Energy). BagcÄ ± carried out a research in 2008 targeted to study the potential of developing a zero energy region in outer Island. Peng Chau was analyzed with different implementations of renewable energy and it is shown that a combination of solar, wind and hydro energy were a possible solution towards an Island that is independent from fossil fuel energy supply (BagcÄ ±, 2009). Despite the researches above, there is little research on full scale analysis on the feasibility of Hydro and Tidal energy in Hong Kong. Therefore it is of interest to determine whether the advances of technologies have gain points for Tidal and Hydro energy as potential alternative energy sources in Hong Kong. Tidal Energy Figure 1. Operating principle of Tidal Barrages (Palmer, 2008) Tidal Energy is a result from gravitational force between celestial body such as the earth, moon, sun etc., as the moon is the nearest among other celestial body, it is usually considered as the only contributor to the tidal formation. The moon rotates around the earth every 27.3 days and the earth rotates along its axis every 24hr. The net effect is that tidal fluctuation occures twice each 24 hour 50 mins, same as the earth rotation period with respect to the earth-moon system (World Energy Council, 2004). The amplitude from such fluctuation is called the tidal range, and is the energy that can be captured through a turbo-generator in tide barrage to produce electricity (Figure 1). It is suggested that Tidal energy can provides 5 % of the electricity generated worldwide (Palmer, 2008). According to the meteorological data provided by the Hong Kong Observatory (HKO), Hong Kong displays a gradual change in tidal characteristics, both in tidal range and tidal occurance of high and low tides travelling from southeast to the northwest across the territory. Within a tidal cycle, Waglan Island is the first to experience high tide and low tide whereas Tsim Bei Tsui is the last. Tsim Bei Tsui however, possess the largest mean tidal range of 1.4m, where Waglan Island and Victoria Habour generally possess a tidal range within 1m. (CEDD, 2002; HKO, 2009) Hydro energy Hydro energy shares the same energy carrier with Tidal energy, in which energy from water flow is captured with a marine turbine to generate electricity. It can be install anywhere as soon as water flow exists. Scales of Hydropower generator can be as large as constructions of dam to micro scales, usually found in small villages. Large scale generators were not considered to be implemented as no suitable sites were avaliable. In the report by EMSD, Hydro-energy were briefly analysed, and it is shown that potential of hydro-power in Hong Kong is relatively low compared to wind and solar energy (EMSD, 2001). Despite the feasilbility of Hydroelectricity dam in Hong Kong, there is a debate on the emission of greenhouse gas via this technology. A few studies had suggested that hydroelectric dam will generate three times more than fossil fuel plant to generate the same amount of electricity, in which plants died underneath an operating dam possess anaerobic digestion, generating a significant amount of GHG, especially in south America tropical (e.g. Brazil, Argentina) where hydroelectricity dam is the main source of renewable energy supply. Therefore the à ¢Ã¢â€š ¬Ã…“cleannessà ¢Ã¢â€š ¬Ã‚  of Hydropower is back in a debate (Graham-Rowe, 2005). Wind energy Wind energy is so well known and well developed that it is seen as the major potential renewable energy source that are viable in Hong Kong. Turbine were driven by wind to produce energy, scale of wind turbine are ranging from 198m high turbine generating 6 MW of electricity to some 2kW in micro size wind turbine. EMSD also analysed the potential sites for the installation of wind turbine, which a wind map was introduced for references by the public (Figure 2). Local applications include the famous 800kW wind turbine installed in Lamma Island, as well as the proposed wind farm in South-eastern Waters (EPD, 2006). Project Description This Project was targeted to review and anaylse the potential of Tidal and Hydro energy, and to compare them to the well developed Wind energy in Hong Kong. Since such energy sources are largely depend on meteorology, it is necessary to analyse as well as meteorological condition to determine which energy source are most suitable in Hong Kong. Moreover it is useful to review on current development of mentioned technologies to provide example for the implementation in Hong Kong. Objectives This project aims to: Give an overview of current energy consumption patterns in Hong Kong Provide an update on researches on Tidal, Hydro and Wind energy, these include Technologies involved and their latest development Overseas examples of application Potential strategy of implementation in Hong Kong Compare each of energy source to analyse their potential in Hong Kong, these include Meteorological assessment and potential energy gain Environmental Impact Assessment Cost Effectiveness / Costing Figure 2. Wind Power Density over the Region of Hong Kong (EMSD, 2001) Scope of Work To determine whether the technologies are competent in mitigation energy crisis in Hong Kong, it is always easier to understand how the locals use their energy, as well as the energy consumption in Hong Kong. Therefore it is reasonable to give a brief overview on energy flow pattern in Hong Kong. Energy source distribution, energy usage by different users can be obtained from the EEO, EMSD. Since Wind energy was well researched and there are a lot of applications in Hong Kong, wind energy will be used as a base for comparison with other technologies encountered in this project. Local and overseas examples will be discussed, as it provides a real life example into the application of such technologies. As mentioned before this project requires a significant amount of meteorological data, therefore meteorological observations from the Hong Kong Observatory (HKO) will be analysed to review the possibilities of implementing tidal, hydro and wind energy. Despite the HKO, observations from the Environmental Central Facilities can also available to the public for detail analysis of wind and tidal observations. (Environmental Central Facility) Lastly, if viable, a cost analysis on some of the technologies can be carry out to demonstrate the economy of such renewable technologies and thus cost effectiveness can be use as an indicator to compare the aforementioned technologies. Time Management This project is mostly a Literature Research Project with some analysis on meteorological observations. Major milestone includes: 31 January, 2010; submission of inception report 30 September, 2010; submission of preliminary findings 21 April, 2011; submission of project title and draft dissertation (tentative), and expression of intention to complete project 30 June, 2011; Oral Presentation (tentative) 8 August, 2011; submission of final dissertation (tentative) Appendix A shows a Gantt chart showing tentative schedule of the project, stating the milestones as well as phases of the project.

The Journey To Becoming A Nurse Nursing Essay

The Journey To Becoming A Nurse Nursing Essay My intellectual interests, academic and, professional objectives encouraged me to pick my field of study in healthcare, to be specific, the profession of nursing. During adolescence, children are encouraged to consider various majors and future career options. Some mature fast and realize their goals during early adolescence, some realize it mid-adolescence and, others late. I was uncertain about my career path during my early stages. However, my passion for the medical field was and still is firm. I come from a family made up physicians, pharmacists, nurses, laboratory technicians, and physician assistants; this, of course, influenced my familiarity with science majors.   With such an interest in mind, I began volunteering in hospitals at a young age, where I was surrounded by patients who approached me for assistance. I was able to assist the patients to the doctors office and always tried to have a conversation with the patient. In such an occurrence, I embraced the feeling of n eed and comfort from those whom I have helped. One notable experience that I have had was caring for my grandmother, who was difficult to cope with due to her massive mood swings and impatience. I knew she trusted and depended on me as she clutched my hands for guidance. At that time I knew I want to definitely take part in medical field. Therefore, I decided to take up field in health care profession after undergraduate studies. Passion, determination, and patience are important key terms to succeed in a health care profession: these characteristics work to my advantage. During my academic life, I continued exploring majors that would fit my goal. After much discussion with my college advisors, I came across Letters, Arts and Sciences at Abington College. As I researched further into the degree, I was sure I wanted to do LASAB. This is my chance to challenge myself by creating my own major that will help me fulfill my requirements for post- graduate studies, in nursing career. This academic helped me to find the way to the right career path that will introduce me to the healthcare world where it ______ me to earn a masters degree after finishing my bachelors. Over the course of my undergraduate studies, I have taken many courses that have helped me grasp the phenomena of science and patient care. College opened a new chapter in my life, a chapter filled with science. I comprehend with the facts and theories of the human body and admire the discoveries of new cause of illness and treatments which becomes a great advantage to the world as a whole. College life has made a great input in my life by helping me enter adulthood and gradually learning to cope with stress, manage time, and make responsible decisions for myself. The four core areas of the Letters, Arts, and Sciences major are Research Methods/ Projects Critical Analysis Communication Skills Theory/ Application Skills The courses that I have chosen to apply to these core requirements will fulfill the requirement for this degree and will benefit me in my planner Nursing career. The skills I gained from these courses are fundamental to becoming successful in a health care profession. Research is a process of study or examination of a subject from different points of view.  I have selected Microbiology 107; Elementary Microbiology Laboratory, and Chemistry 111 and 113; Experimental Chemistry to the Research Methods/ Projects to fulfill the core requirement. Microbiology 107: Elementary Microbiology Laboratory gave me an introduction about microbes. I learned the importance and the proper handling of microorganisms through demonstrations and working on each experiment. The lab has also helped me to identify and count bacteria, effects of chemical and physical agents on microorganisms. This course has helped me learn the importance of controlling microbial growth on peoples bodies and how failure to do so can lead to the spread of disease, especially in the hospital setting. Chemistry 111 and 113: Experimental Chemistry introduced me to chemicals and challenging experiments. It helped me better understand how to interpret data about various experiments that dealt with introductory chemistry. I learned to write a formal laboratory report, interpretation of data using statistics, and an appreciation for what instruments can do. Each of these courses will help me focus on areas that are relevant in the medical field. International Studies 100 fulfills to the Critical Analysis core requirement.  I believe it is important to be able to understand people and their background/culture, especially when working in the health-care profession. There is a great chance of meeting people from different diversity in my field. As a health care professional, I must learn and know about patients cultures while I treat them. This course has given me a basic understanding of the many cultures and their global issues, such as financial crisis, racism, health issues, and human rights issues. This course helped me to connect with different cultures, their domestic issues, and responses to human rights violations. In a hospital setting, health care professionals are faced with patients that have many different issues and one main issue would be race. Health-care professionals must understand that all come from different culture with different issues; therefore, we should not be judged by the race because we are all humans. We must treat people equally. We will be able to connect to patients better and help them deal with their illnesses better if we are knowledgeable about their culture. The course will help me to understand everyone better.   I apply INART001, Integrative Arts into the core requirement of communications skills. This course helped me to develop critical perception, knowledge, and judgments through examining the basic arts through communication. Communication is very important and this course helped me to communicate in both art and non- art situations. When one thinks of the health care, a complex array of professions come into mind. In order for all these professions to provide the best possible care for their patients, communication between them is vital. For example, suppose a patient has a penicillin allergy and the doctor ordered a medication that is a penicillin derivative. In that case, the pharmacist calls the doctor and a new medication is prescribed. This course helped me communicate in simple way that others will understand and gave me more confident. During my internship at the hospital, I noticed that communication is very important and presenting a simple communication will help the patie nt understand the nurse better. On the other side, Integrative arts such as art, music, dance or drama introduced as Art therapy in health care. This therapy was used to help child survivors of Hurricane Katrina overcome mental traumas and people with schizophrenia BBC news.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  I place Anthropology 45, Cultural anthropology to the core requirement of Theory/Application skills. As I mentioned earlier, it is important to be able to understand people when working in the health-care profession. All societies have rules, standards, conventions and beliefs. Studying anthropology allowed me to understand how social culture work. As a health care professional, it is important to understand the society, government, religion and their culture. This course focused on human culture; I learned to appreciate cultural diversity. An in-depth knowledge into the human culture is especially important in todays health care, especially in a diverse country like the United States. Take, for example, the culture of Jehovahs Witnesses. This denomination prohibits blood transfusions for their believers. Respecting their wishes, hospitals now have bloodless surgeries where newer techniques have been developed that do not require blood transfusions, even for m ajor invasive surgeries like coronary artery bypass graft. Also in this day, a healthcare provider sees patients from various countries and various cultures. Something considered elementary in a culture might be considered taboo in another. For example, in the American society women have the same rights as men and considered capable to make their own decisions, as where in some cultures, its the man who makes the decisions in the family. In cases like this a healthcare provider must respect the differences and work with their patient to provide what is the best possible care for their female patients. Therefore, I must understand the rules and beliefs of other cultures so I can understand the patients better.   Everyday people face many different types of problems. It could be physical, emotional or mental stress. As a health care professional, it is important to understand the reasons for those problems and assisting the exact treatment Psychology is the science that enables me to connect to an individual through the mind to understand and deal with the mental processes and behavior of individual human beings. I have chosen five 400 level courses from three areas that relate to my theme. Those are Kinesiology 445: Alcohol and Drug Education, Psychology 470: Abnormal Psychology, Psychology 424: Applied Social psychology, Counselor Education 401: Foundations of Chemical Dependency Counseling, and Biology 495. Kinesiology 445: Alcohol and Drug Education helped me to understand and learn more about many types of drugs and alcohol uses not only in the American society but worldwide. Moreover, it has taught the drug physiology, drug-related health effects and issues related to social and psychological effects of drug use and abuse. Alcohol and Drug can affect peoples lives so fast. I did a research paper about Alcohol and drug, as part of the research I surveyed twenty neighbors and 80% of them addicted to alcohol and drugs. Most of them were addicted due to stress but some of them started out as a fun hobby. Many people find Alcohol and Drug as a solution to their problems. Therefore, I will definitely come across many patients that are addicted to alcohol and drugs. I am sure I am able to use the fundamental information from this course and apply it to the patients I might come across in my professional field. Another challenging course was Psychology 470: Abnormal Psychology has taught me the understanding of types of abnormal experience and behavior personality, as well as mental and psychotic disorders that impact multiple areas of a human life that might not be able to be diagnosed on a personal basis.  The most common disorders are Schizophrenia, Bipolar Disorder, Eating disorder, Autistic Disorder, Borderline personality disorder and Obsessive-Compulsive Disorder. This course is mostly focused on the identification, treatment and understanding of abnormal behavior and psychopathology. It taught me the different diagnoses of types of behaviors, and it will definitely help me in my health profession, especially if I decided work on psychiatric department. Psychology 424: Applied Social psychology, gave me an overview of social psychological theories and research methods to field settings and to the study of social issues. It taught me how to conduct a survey and analyze a report based on a study. It has also helped me to understand the social life and how psychology applied to social life every day. Especially in health care settings, I must apply social psychology to understand social and practical problems thats happening around us. I must be motivated , making sense of my co-workers, social perceptions, and understanding the bias order for me to perform a satisfaction job that will draws a general impression for my characteristic such as intelligence. Counselor Education 401: Foundations of Chemical Dependency Counseling introduced me to the concept related to drug and alcohol dependency, diagnosis and assessment, its prevention, counseling and treatment of dependencies. It has helped me to understand how to deal with that are addicted to various types of drugs like cocaine, heroin, and methamphetamines. A person becomes chemically dependent due to several factors such as environment, psychological, or genetic. Health care provide residential, outpatient, extended, and aftercare treatments for someone who is chemically dependent. On the other side, Twelve-Step meetings are available for those who interested in self-help recovery. I was assigned to attend a Twelve-Step meeting for Alcoholics Anonymous(AA). The stores that I heard during the meetings were depressing because they were so addicted to alcohol and regret their past. This meeting is part of the treatment to be sober. Chemical dependency is chronic and can be fatal. Somet imes, chemical dependency affects health care professionals and co-workers are aware of the signs and symptoms. I have selected Nutrition 251, Sociology 035, and Biology 110 to full fill the humanities and the social science area. Nutrition 251, Introductory Principles of Nutrition, is a course that gave me more knowledge on principles of nutrition. This course broadens my knowledge about the physiological functions and food sources that related to human growth. It helped me to focus on my nutrition better and stay healthier. Especially in healthcare, it is important to make sure the patient is getting the right amount of nutrition. If the patients nutrition is imbalanced, it can cause diarrhea and risk of infection. Therefore all the knowledge that I learned from this class about nutrition will help me to provide a better nutrition life style to my patients. Sociology 035, is the study of aging in older people. The common beliefs, aspects of aging, how economy and family influence the aging process. The course helped me to be more kind, warm and practical with people .A nurse must be kind, sympathetic and compassionate because when I work with patients it will give me better knowledge on how to deal with everyone. I have compared facts that I learned from this class with my parents and grandparents behavior, which helped me understand them better. For example, as my grandparent get old, the chances of them listening to their kids are rare. Even if they are right or wrong , they want the kids to accept it. Once the kids get married and leave the house, the parents starting a new life where they are bonding more to each other. Thats something I have noticed in my grandparents life. All the knowledge that I acquired from this course will help me understand older peoples relation to others and how they would accept the world to live their li fe. Biology 110, Basic Concepts and Biodiversity, taught me the foundation of the basic concept of evolution. It gave me an understanding of living organisms, how genetic processes provide continuity between generations and how evolutionary processes take place. This course includes both lecture and lab. It is the study of living organisms; all life depends on certain physiological and chemical functions. To work in healthcare you must have a basic understanding of the underlying principles of life. These courses that I have listed above are important in my future education that I plan on focusing on after graduation. In health care, it is critical that students understand any individuals different characteristics and behaviors before I respond to patients symptoms. As a capstone course: BIOL 495, I have an internship, at Temples Jeanes Hospital in North East Philadelphia a. As an intern at the hospital, I have been assigned to the same day surgery unit department with patients. This opportunity will also allow me to work with professional staff and patients. It is my duty to go to each patient to check on them to make sure they are doing great because they are recovering from the surgery. Sometimes they would ask juice/water and some of them might need to use the rest room so it is my responsibility to take care of them. Meanwhile, I go with the nurses to each patients room when they go over the surgery procedures and learn how pre admission is done on a patient. I will be attending to the needs of patients that are undergoing different procedures and an opportunity to interact with surgeons, physician assistants, and nurses. It also will be hands on experience with all the skills and materials that I have learned in the courses that I have lis ted in this proposal   In conclusion, I feel that my education has shaped my life to what is today and these courses listed have gave me a better understanding about medical issues happening in this world. Health care profession is not a relaxing profession but demanding and stressful occupation, yet I am ready to face the various situations I may be in and become stronger and wiser in my profession and as a person. It is also a profession where every day I am guaranteed to touch a life or be touched by the lives of others. Letters, Arts, and Sciences at Abington will help me reach my goals after my undergraduate education is complete.